Enhanced human enterovirus 71 infection by endocytosis inhibitors reveals multiple entry pathways by enterovirus causing hand-foot-and-mouth diseases

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منابع مشابه

Molecular Detection of Human Enterovirus 71 Causing Hand, Foot and Mouth Disease in Klang Valley, Malaysia

Hand, Foot and Mouth Disease (HFMD) is a childhood infection caused by Enterovirus 71 (EV71) or Coxsackievirus A16 (CA16). Occasionally, Enterovirus 71 becomes fatal and causes encephalitis. The objective of the present study was to determine HFMD caused by Enterovirus 71 if prevalent in the Klang Valley, Malaysia. 184 specimens were collected from the patients reported to University Kebangsaan...

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Epidemic Hand, Foot and Mouth Disease Caused by Human Enterovirus 71, Singapore

Singapore experienced a large epidemic of hand, foot and mouth disease (HFMD) in 2000. After reviewing HFMD notifications from doctors and child-care centers, we found that the incidence of HFMD rose in September and declined at the end of October. During this period, 3,790 cases were reported. We performed enteroviral cultures on 311 and 157 specimens from 175 HFMD patients and 107 non-HFMD pa...

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Proteomic analysis of extremely severe hand, foot and mouth disease infected by enterovirus 71

BACKGROUND To clarify the molecular mechanisms that participate in the severe hand, foot and mouth disease (HFMD) infected by Enterovirus 71 and to detect any related protein biomarkers, we performed proteomic analysis of protein extracts from 5 extremely severe HFMD children and 5 healthy children. METHODS The protein profiles of them were compared using two-dimensional electrophoresis. Diff...

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ژورنال

عنوان ژورنال: Virology Journal

سال: 2018

ISSN: 1743-422X

DOI: 10.1186/s12985-017-0913-3